3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid

3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN) is a sialic acid. 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid protects the oligo/ (poly) sialyl chains from exosialidases at nonreducing terminal, and plays a role in egg activation of salmonid fish[1]. 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid is abundant in fetal cord red blood cells and malignant human ovarian cancer cells[2].

Product Specifications

CAS Number

[153666-19-4]

Product Name Alternative

KDN

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/3-deoxy-d-glycero-d-galacto-2-nonulosonic-acid.html

Purity

99.90

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

OC[C@@H](O)[C@H]([C@]1([H])OC(O)(C[C@@H]([C@H]1O)O)C(O)=O)O

Molecular Formula

C9H16O9

Molecular Weight

268.22

References & Citations

[1]Nadano D, et al., A naturally occurring deaminated neuraminic acid, 3-deoxy-D-glycero-D-galacto-nonulosonic acid (KDN) . Its unique occurrence at the nonreducing ends of oligosialyl chains in polysialoglycoprotein of rainbow trout eggs. J Biol Chem. 1986 Sep 5;261 (25) :11550-7.|[2]Inoue S, et al., Identification of free deaminated sialic acid (2-keto-3-deoxy-D-glycero-D-galacto-nononic acid) in human red blood cells and its elevated expression in fetal cord red blood cells and ovarian cancer cells. J Biol Chem. 1998 Oct 16;273 (42) :27199-204.