BMf-BH3
BMf-BH3 (BMF-Y) belongs to the Bcl-2 apoptosis mediator family. BH3-only protein, Bmf is a key molecule for histone deacetylase (HDAC) inhibitors mediated enhancing effect on ionizing radiation-induced cell death[1][2].
Product Specifications
Product Name Alternative
BMF-Y
UNSPSC
12352209
Target
Apoptosis
Type
Peptides
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bmf-bh3.html
Solubility
10 mM in DMSO
Smiles
O=C(C)N[C@@H](CC1=CN=CN1)C(N[C@H](CCC(N)=O)C(N[C@@H](C)C(N[C@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@H](CCC(N)=O)C(NC([C@@H](C)CC)C(N[C@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(NC([C@H](CC)C)C(N[C@@H](C)C(N[C@H](CC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](C(N[C@@H](CC2=CN=CN2)C(N[C@H](CCCNC(N)=N)C(N[C@@H](CC3=CC=C(O)C=C3)C(N)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C117H185N37O31
Molecular Weight
2605.95
References & Citations
[1]Zhang Y, et al. Bmf contributes to histone deacetylase inhibitor-mediated enhancing effects on apoptosis after ionizing radiation. Apoptosis. 2006 Aug;11 (8) :1349-57.|[2]Puthalakath H, et al. Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis. Science. 2001 Sep 7;293 (5536) :1829-32.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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