Dimethyl-bisphenol A
Dimethyl-bisphenol A (DMBPA) is a potent HIF-1α inhibitor. Dimethyl-bisphenol A can decrease Vegfa mRNA expression[1].
Product Specifications
CAS Number
[1568-83-8]
Product Name Alternative
DMBPA
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HIF/HIF Prolyl-Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dimethyl-bisphenol-a.html
Concentration
10mM
Purity
99.78
Solubility
DMSO : ≥ 100 mg/mL
Smiles
COC(C=C1)=CC=C1C(C)(C)C(C=C2)=CC=C2OC
Molecular Formula
C17H20O2
Molecular Weight
256.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Diana P Trebec-Reynolds, et al. VEGF-A expression in osteoclasts is regulated by NF-kappaB induction of HIF-1alpha. J Cell Biochem. 2010 May 15;110 (2) :343-51.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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