N6-Methyladenosine

N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.

Product Specifications

CAS Number

[1867-73-8]

Product Name Alternative

6-Methyladenosine; N-Methyladenosine

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Influenza Virus

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/N6-Methyladenosine.html

Concentration

10mM

Purity

99.84

Solubility

DMSO : ≥ 31 mg/mL|H2O : 5.56 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C3=C(N=C2)C(NC)=NC=N3

Molecular Formula

C11H15N5O4

Molecular Weight

281.27

Precautions

H302, H315, H319, H335

References & Citations

[1]Wang X, et al. N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014 Jan 2;505 (7481) :117-20.|[2]Li Y, et al. Genome-wide detection of high abundance N6-methyladenosine sites by microarray. RNA. 2015 Aug;21 (8) :1511-8.|[3]Dang W, et al. N6-Methyladenosine and Viral Infection. Front Microbiol. 2019 Mar 5;10:417.