RIPGBM
RIPGBM is a selective inducer of apoptosis in glioblastoma multiforme (GBM) cancer stem cells (CSCs) with an EC50 of ≤500 nM[1].
Product Specifications
CAS Number
[355406-76-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/RIPGBM.html
Purity
99.95
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
CC(N(C(C1=O)=C(NCC2=CC=CC=C2)C(C3=C1C=CC=C3)=O)CC4=CC=C(F)C=C4)=O
Molecular Formula
C26H21FN2O3
Molecular Weight
428.45
Precautions
H302, H315, H319
References & Citations
[1]Lucki NC, et al. A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer. Proc Natl Acad Sci U S A. 2019 Mar 26;116 (13) :6435-6440.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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