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SGC-UBD253

Product Specifications

UNSPSC Description

SGC-UBD253 is a potent HDAC6-UBD antagonist. SGC-UBD253 can be used in research of cancer[1].

Target Antigen

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage;Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sgc-ubd253.html

Solubility

DMSO : 10 mg/mL (ultrasonic;warming)

Smiles

O=C(O)CCC(N1CC(NCC2=CC=CC=C2OC)=O)=NC3=C(C=CC=C3Cl)C1=O

Molecular Weight

429.85

References & Citations

[1]Harding RJ, et, al. Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6. J Med Chem. 2023 Aug 10;66(15):10273-10288.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-155697/SGC-UBD253-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-155697/SGC-UBD253-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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