SGC-UBD253
SGC-UBD253, a chemical probe, is a potent HDAC6-UBD antagonist. SGC-UBD253 can be used in research of cancer[1].
Product Specifications
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sgc-ubd253.html
Purity
99.3
Solubility
DMSO : 10 mg/mL (ultrasonic; warming)
Smiles
O=C(O)CCC(N1CC(NCC2=CC=CC=C2OC)=O)=NC3=C(C=CC=C3Cl)C1=O
Molecular Formula
C21H20ClN3O5
Molecular Weight
429.85
References & Citations
[1]Harding RJ, et, al. Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6. J Med Chem. 2023 Aug 10;66 (15) :10273-10288.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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