Ac-YEVD-AMC
Ac-YEVD-AMC is a fluorescent substrate of caspase-1/11. Ac-YEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection when treating with cell lysate[1].
Product Specifications
CAS Number
[1631716-11-4]
UNSPSC
12352209
Target
Fluorescent Dye
Type
Peptides
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ac-yevd-amc.html
Purity
99.59
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C=C(C2=CC=C(C=C2O1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(C)=O)CC3=CC=C(O)C=C3)=O)CCC(O)=O)=O)C(C)C)=O)CC(O)=O)=O)C
Molecular Formula
C35H41N5O12
Molecular Weight
723.73
References & Citations
[1]Havira MS, et al. Shiga toxin suppresses noncanonical inflammasome responses to cytosolic LPS. Sci Immunol. 2020 Nov 27;5 (53) :eabc0217.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
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