Diopterin

6807-82-5

Pteroyl diglutamic acid; Folate monoglutamate

12352005

Antifolate

Reference compound

Cell Cycle/DNA Damage

Cancer-programmed cell death

Cancer

https://www.medchemexpress.com/diopterin.html

O=C(CC[C@H](NC([C@@H](NC(C1=CC=C(C=C1)NCC2=CN=C3NC(N)=NC(C3=N2)=O)=O)CCC(O)=O)=O)C(O)=O)O

C24H26N8O9

570.51

[1]Rothenberg SP, et al. Further observations on the folate-binding factor in some leukemic cells. J Clin Invest. 1971 Mar;50 (3) :719-26.

Room temperature

Reference compound1

Phase 1