15-PGDH-IN-3
15-PGDH-IN-3 (Compound 61) is a selective competitive inhibitor of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) [1].
Product Specifications
CAS Number
355827-05-3
UNSPSC
12352005
Target
15-PGDH
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/15-pgdh-in-3.html
Solubility
10 mM in DMSO
Smiles
BrC1=CNC2=NC(SCC3=CC=CC=C3C#N)=NC2=C1
Molecular Formula
C14H9BrN4S
Molecular Weight
345.22
References & Citations
[1]Niesen FH, et al. High-affinity inhibitors of human NAD-dependent 15-hydroxyprostaglandin dehydrogenase: mechanisms of inhibition and structure-activity relationships. PLoS One. 2010 Nov 2;5 (11) :e13719.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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