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15-PGDH-IN-3

15-PGDH-IN-3 (Compound 61) is a selective competitive inhibitor of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) [1].

Product Specifications

CAS Number

355827-05-3

UNSPSC

12352005

Target

15-PGDH

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/15-pgdh-in-3.html

Solubility

10 mM in DMSO

Smiles

BrC1=CNC2=NC(SCC3=CC=CC=C3C#N)=NC2=C1

Molecular Formula

C14H9BrN4S

Molecular Weight

345.22

References & Citations

[1]Niesen FH, et al. High-affinity inhibitors of human NAD-dependent 15-hydroxyprostaglandin dehydrogenase: mechanisms of inhibition and structure-activity relationships. PLoS One. 2010 Nov 2;5 (11) :e13719.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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