Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Serpinin

Serpinin is an agonist of the protease inhibitor Nexin-1 (PN-1) . Serpinin upregulates the expression of PN-1 through the cAMP-PKA-Sp1 signaling pathway, promoting granule biogenesis in endocrine cells. Serpinin is used in research related to the regulation of secretory function[1]. Serpinin is a selective agonist for β-adrenergic receptors. Serpinin interacts with β1-adrenergic receptors to activate the AC-cAMP-PKA pathway, which regulates myocardial systolic and diastolic function. pGlu-serpinin upregulates Bcl2 mRNA transcription and exerts neuroprotective effects[2].

Product Specifications

CAS Number

1383743-23-4

UNSPSC

12352209

Target

Serpin

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/serpinin.html

Purity

98.74

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]2NCCC2

Molecular Formula

C125H204N32O46

Molecular Weight

2891.14

References & Citations

[1]Koshimizu H, et al. Serpinin: a novel chromogranin A-derived, secreted peptide up-regulates protease nexin-1 expression and granule biogenesis in endocrine cells. Mol Endocrinol. 2011 May;25 (5) :732-44. |[2]Loh YP, et al. Chromogranin A and derived peptides in health and disease. J Mol Neurosci. 2012 Oct;48 (2) :347-56.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Tceal8 Mouse Gene Knockout Kit (CRISPR)
KN517310 1 Kit

Tceal8 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
C10orf105 (NM_001168390) Human Over-expression Lysate
LC432566 20 µg

C10orf105 (NM_001168390) Human Over-expression Lysate

Sign In for Pricing
View Details
NDRG2 (N-term) Rabbit Polyclonal Antibody
AP52834PU-N 400 µL

NDRG2 (N-term) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
2-[2-[2-[2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl]ethoxy]ethoxy]ethoxy]ethanol Dihydrochloride
TRC-D418686-10MG 10 mg

2-[2-[2-[2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl]ethoxy]ethoxy]ethoxy]ethanol Dihydrochloride

Sign In for Pricing
View Details
Anti Human EIF4E Polyclonal
Y055215 100 µL

Anti Human EIF4E Polyclonal

Sign In for Pricing
View Details
(S)-Aclidinium Bromide
TRC-A190190-50MG 50 mg

(S)-Aclidinium Bromide

Sign In for Pricing
View Details