VEGFR-2-IN-29
VEGFR-2-IN-29 (Compound 5) is a VEGFR-2 inhibitor with an IC50 of 16.5 nM[1].
Product Specifications
CAS Number
[62802-77-1]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vegfr-2-in-29.html
Purity
99.36
Solubility
DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC1=C2N=CC=CC2=CC=C1)C3=CC=CC([N+]([O-])=O)=C3
Molecular Formula
C16H11N3O3
Molecular Weight
293.28
Precautions
H315, H319
References & Citations
[1]Yang Y, et al. Design, synthesis and biological evaluation of quinoline amide derivatives as novel VEGFR-2 inhibitors. Bioorg Med Chem Lett. 2010 Nov 15;20 (22) :6653-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
VEGFR2/KDR/Flk-1
Available Sizes
Curated Selection
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