(-)-Menthol
Product Specifications
UNSPSC Description
(-)-Menthol is a key component of peppermint oil that binds and activates transient receptor potential melastatin 8 (TRPM8), a Ca2+-permeable nonselective cation channel, to increase [Ca2+]i[1]. Antitumor activity[1].
Target Antigen
Endogenous Metabolite; TRP Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/_-_-Menthol.html
Purity
99.88
Solubility
DMSO : 100 mg/mL (ultrasonic)|H2O : 1.89 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O[C@H]1[C@H](C(C)C)CC[C@@H](C)C1
Molecular Weight
156.27
References & Citations
[1]Park EJ, et al. Menthol Enhances an Antiproliferative Activity of 1alpha,25-Dihydroxyvitamin D(3) in LNCaP Cells. J Clin Biochem Nutr. 2009 Mar;44(2):125-30.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-75161/minus-Menthol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-75161/minus-Menthol-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
2216-51-5
Available Sizes
Curated Selection
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