Heterophyllin B
Heterophyllin B is an active cyclic peptide isolated from Pseudostellaria heterophylla. Heterophyllin B provides a novel strategy for the treatment of esophageal cancer[1].
Product Specifications
CAS Number
145459-19-4
UNSPSC
12352005
Hazard Statement
H315, H319
Target
PI3K
Type
Natural Products
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/heterophyllin-b.html
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@@](CCC1)([H])N1C([C@](NC(CNC(CNC2=O)=O)=O)([H])CC(C)C)=O)N(CCC3)[C@]3([H])C(N(CCC4)[C@]4([H])C(N[C@@](C(N[C@H]2CC5=CC=CC=C5)=O)([H])[C@@H](C)CC)=O)=O
Molecular Formula
C40H58N8O8
Molecular Weight
778.94
Precautions
H315, H319
References & Citations
[1]Tantai JC, et al. Heterophyllin B inhibits the adhesion and invasion of ECA-109 human esophageal carcinoma cells by targeting PI3K/AKT/β-catenin signaling. Mol Med Rep. 2016 Feb;13 (2) :1097-104.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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