Emodin
Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction[1]. Emodin inhibits casein kinase-2 (CK2) . Anti-inflammatory and anticancer effects[2]. Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice[3].
Product Specifications
CAS Number
518-82-1
Product Name Alternative
Frangula emodin
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
11β-HSD; Autophagy; Casein Kinase; SARS-CoV
Type
Natural Products
Related Pathways
Anti-infection; Autophagy; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Emodin.html
Purity
99.39
Solubility
Acetone : 10.87 mg/mL (ultrasonic) |DMSO : 5.41 mg/mL (ultrasonic) |Ethanol : < 1 mg/mL (ultrasonic)
Smiles
O=C1C2=C(C=C(C)C=C2O)C(C3=CC(O)=CC(O)=C31)=O
Molecular Formula
C15H10O5
Molecular Weight
270.24
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
CK2
Available Sizes
Frequently Asked Questions
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