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NFAT Transcription Factor Regulator-1

NFAT Transcription Factor Regulator-1 is an IL-2 synthesis inhibitor with an IC50 of 182 nM.

Product Specifications

CAS Number

245747-71-1

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Interleukin Related

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/NFAT_Transcription_Factor_Regulator.html

Purity

99.37

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=C(F)C=NC=C1)NC2=CC=C(N3N=C(C(F)(F)F)C=C3OC(F)F)C=C2

Molecular Formula

C17H10F6N4O2

Molecular Weight

416.28

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Djuric SW, et al. 3,5-Bis (trifluoromethyl) pyrazoles: a novel class of NFAT transcription factor regulator. J Med Chem. 2000 Aug 10;43 (16) :2975-81.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

IL-2; IL-4; IL-5

Available Sizes

Frequently Asked Questions

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