NFAT Transcription Factor Regulator-1
NFAT Transcription Factor Regulator-1 is an IL-2 synthesis inhibitor with an IC50 of 182 nM.
Product Specifications
CAS Number
[245747-71-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/NFAT_Transcription_Factor_Regulator.html
Purity
99.37
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C(F)C=NC=C1)NC2=CC=C(N3N=C(C(F)(F)F)C=C3OC(F)F)C=C2
Molecular Formula
C17H10F6N4O2
Molecular Weight
416.28
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Djuric SW, et al. 3,5-Bis (trifluoromethyl) pyrazoles: a novel class of NFAT transcription factor regulator. J Med Chem. 2000 Aug 10;43 (16) :2975-81.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-2; IL-4; IL-5
Available Sizes
Curated Selection
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