Recombinant Human Claudin-6 Protein VLP

<strong>Recombinant Human Claudin-6 Protein VLP</strong>_x000D_ <strong>Catalog number:</strong> B2019117_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 23.30 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −80°C_x000D_ <strong>Keywords:</strong> UNQ757/PRO1488 Protein, Human_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Wu Q, Liu Y, Ren Y, Xu X, Yu L, Li Y, Quan C. Tight junction protein, claudin-6, downregulates the malignant phenotype of breast carcinoma Eur J Cancer Prev. 2010 May;19(3):186-94._x000D_ 2: Zavala-Zendejas VE, Torres-Martinez AC, Salas-Morales B, Fortoul TI, Montaño LF, Rendon-Huerta EP. Claudin-6, 7, or 9 overexpression in the human gastric adenocarcinoma cell line AGS increases its invasiveness, migration, and proliferation rate Cancer Invest. 2011 Jan;29(1):1-11._x000D_ 3: Turksen K, Troy TC. Claudin-6: a novel tight junction molecule is developmentally regulated in mouse embryonic epithelium Dev Dyn. 2001 Oct;222(2):292-300._x000D_ 4: Wu Q, Liu YF, Ren Y, Xu XM, Yu LN, Li YL, Quan CS. [Effects of stable up-regulation of tight junction protein claudin-6 upon biological phenotypes of breast cancer cell MCF-7] Zhonghua Yi Xue Za Zhi. 2010 Feb 9;90(6):407-12._x000D_ 5: Guo Y, Xu X, Liu Z, Zhang T, Zhang X, Wang L, Wang M, Liu Y, Lu Y, Liu Y, Quan C. Apoptosis signal-regulating kinase 1 is associated with the effect of claudin-6 in breast cancer Diagn Pathol. 2012 Aug 27;7:111._x000D_ 6: Nishikiori N, Sawada N, Ohguro H. Prevention of murine experimental corneal trauma by epigenetic events regulating claudin 6 and claudin 9 Jpn J Ophthalmol. 2008 May-Jun;52(3):195-203._x000D_ 7: Martovetsky G, Bush KT, Nigam SK. Kidney versus Liver Specification of SLC and ABC Drug Transporters, Tight Junction Molecules, and Biomarkers Drug Metab Dispos. 2016 Jul;44(7):1050-60._x000D_ 8: Sas D, Hu M, Moe OW, Baum M. Effect of claudins 6 and 9 on paracellular permeability in MDCK II cells Am J Physiol Regul Integr Comp Physiol. 2008 Nov;295(5):R1713-9._x000D_ 9: Toth G, Zraly CB, Thomson TL, Jones C, Lapetino S, Muraskas J, Zhang J, Dingwall AK. Congenital anomalies and rhabdoid tumor associated with 22q11 germline deletion and somatic inactivation of the SMARCB1 tumor suppressor Genes Chromosomes Cancer. 2011 Jun;50(6):379-88._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/38776391">10: Stadler CR, Ellinghaus U, Fischer L, Bähr-Mahmud H, Rao M, Lindemann C, Chaturvedi A, Scharf C, Biermann I, Hebich B, Malz A, Beresin G, Falck G, Häcker A, Houben A, Erdeljan M, Wolf K, Kullmann M, Chang P, Türeci Ö, Şahin U. Preclinical efficacy and pharmacokinetics of an RNA-encoded T cell-engaging bispecific antibody targeting human claudin 6 Sci Transl Med. 2024 May 22;16(748):eadl2720. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant Human Claudin-6 Protein VLP can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>