Ac-DEVD-CMK (TFA)
Ac-DEVD-CMK (Caspase-3 Inhibitor III) TFA is a selective and irreversible caspase-3 inhibitor. Ac-DEVD-CMK TFA significantly inhibits apoptosis induced by high levels of glucose or 3,20-dibenzoate (IDB; HY-137295). Ac-DEVD-CMK TFA can be used in a variety of experimental approaches to inhibit apoptosis[1][2][3].
Product Specifications
Product Name Alternative
Caspase-3 Inhibitor III (TFA)
UNSPSC
12352209
Target
Apoptosis; Caspase
Type
Peptides
Related Pathways
Apoptosis
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ac-devd-cmk-tfa.html
Purity
99.07
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClCC([C@H](CC(O)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CC(O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
Molecular Formula
C23H32ClF3N4O13
Molecular Weight
664.97
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported
Citation 01
J Agric Food Chem. 2025 Aug 27;73 (34) :21296-21308.|PLoS Pathog. 2024 Jul 22;20 (7) :e1012408.|Exp Neurol. 2024 Mar:373:114678.
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