Amthamine (dihydrobromide)
Amthamine is a histamine receptor (H1R-H4R) agonist. Amthamine can produce liver congestion and necrosis of liver cells. Amthamine can be used to study the induction effect of H1R-H4 agonist on hepatotoxicity [1].
Product Specifications
CAS Number
142457-00-9
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/amthamine-dihydrobromide.html
Purity
99.64
Solubility
DMSO : 83.33 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
NCCC1=C(C)N=C(N)S1.Br.Br
Molecular Formula
C6H13Br2N3S
Molecular Weight
319.07
Precautions
H302, H315, H319, H335
References & Citations
[1]Trivendra Tripathi, et al. Hepatotoxicity Due to Histamine Trifluoro-Methyl Toluidide, Amthamine, R- (-) -α-Methyl Histamine and Clobenpropit (H1R-H4R-Agonists, Respectively) in Rabbit Experimental Model. American Medical Journal. 2010, 1 (1) : 1-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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