Amthamine (dihydrobromide)

Amthamine is a histamine receptor (H1R-H4R) agonist. Amthamine can produce liver congestion and necrosis of liver cells. Amthamine can be used to study the induction effect of H1R-H4 agonist on hepatotoxicity [1].

Product Specifications

CAS Number

[142457-00-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/amthamine-dihydrobromide.html

Purity

99.64

Solubility

DMSO : 83.33 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

NCCC1=C(C)N=C(N)S1.Br.Br

Molecular Formula

C6H13Br2N3S

Molecular Weight

319.07

Precautions

H302, H315, H319, H335

References & Citations

[1]Trivendra Tripathi, et al. Hepatotoxicity Due to Histamine Trifluoro-Methyl Toluidide, Amthamine, R- (-) -α-Methyl Histamine and Clobenpropit (H1R-H4R-Agonists, Respectively) in Rabbit Experimental Model. American Medical Journal. 2010, 1 (1) : 1-7.