Saroglitazar (magnesium)
Product Specifications
UNSPSC Description
Saroglitazar magnesium is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively.
Target Antigen
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Saroglitazar-Magnesium.html
Purity
98.85
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CCO([Mg+2]1(O(CC)[C@H](C([O-]1)=O)CC2=CC=C(OCCN3C(C)=CC=C3C4=CC=C(SC)C=C4)C=C2)[O-]C5=O)[C@H]5CC6=CC=C(OCCN7C(C)=CC=C7C8=CC=C(SC)C=C8)C=C6
Molecular Weight
901.42
References & Citations
[1]Jain MR, et al. Saroglitazar, a novel PPARα/γ agonist with predominant PPARα activity, shows lipid-lowering effects in preclinical models. Pharmacol Res Perspect. 2015 Jun;3(3):e00136.BMC Complement Med Ther. 2021 Apr 10;21(1):118.|Patent. US20210275504A1.|Cell Biol Toxicol. 2020 Jul 1. |Patent. US20190388398A1.|SSRN. 2024 May 30.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-19937A/Saroglitazar-magnesium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19937A/Saroglitazar-magnesium-SDS-MedChemExpress.pdf
Clinical Information
Phase 4
CAS Number
1639792-20-3
Available Sizes
Curated Selection
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