Saroglitazar (magnesium)
Saroglitazar magnesium is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively.
Product Specifications
CAS Number
[1639792-20-3]
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Saroglitazar-Magnesium.html
Purity
98.85
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CCO([Mg+2]1(O(CC)[C@H](C([O-]1)=O)CC2=CC=C(OCCN3C(C)=CC=C3C4=CC=C(SC)C=C4)C=C2)[O-]C5=O)[C@H]5CC6=CC=C(OCCN7C(C)=CC=C7C8=CC=C(SC)C=C8)C=C6
Molecular Formula
C50H56MgN2O8S2
Molecular Weight
901.42
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 4
Isoform
PPARα; PPARγ
Citation 01
Available Sizes
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RSK1, phosphorylated (Ser363) (Ribosomal S6 Kinase 1, RSK-1, 90kD Ribosomal Protein S6 Kinase 1, p90-RSK 1, p90RSK1, p90S6K, MAP Kinase-activated Protein Kinase 1a, MAPK-activated Protein Kinase 1a, MAPKAP Kinase 1a, MAPKAPK1A, MAPKAPK-1a, Ribosomal Protein S6 Kinase alpha-1, RPS6KA1, S6K-alpha-1) (MaxLight 550) discontinued
