VcMMAE-Deruxtecan

VcMMAE-Deruxtecan (SMP-54418) is a Drug-Linker Conjugates for ADC, which is composed of a linker and a toxic molecule MMAE (HY-15162) (Microtubule inhibitor) and Exatecan (HY-13631) (DNA topoisomerase I inhibitor) . VcMMAE-Deruxtecan can be used for ADC synthesis.

Product Specifications

CAS Number

[2760408-75-9]

Product Name Alternative

SMP-54418

UNSPSC

12352203

Target

Drug-Linker Conjugates for ADC; Microtubule/Tubulin; Topoisomerase

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/vcmmae-deruxtecan.html

Purity

98.10

Solubility

DMSO : 50 mg/mL

Smiles

CC(C)[C@@H](C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N2[C@@]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C3=CC=CC=C3)=O)([H])CCC2)=O)C)=O)=O)=O)C=C1)=O)=O)NC(C(NC(CCCCCN4C(C=CC4=O)=O)=O)CC(C=C5)=CC=C5OCC(NCC(NCC(N[C@@H](CC6=CC=CC=C6)C(NCC(NCOCC(N[C@@H]7C8=C9C(C(N%10C9)=CC([C@](O)(C(OC%11)=O)CC)=C%11C%10=O)=NC%12=CC(F)=C(C)C(CC7)=C%128)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C121H159FN20O28

Molecular Weight

2360.67

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Dual payloads; Topo I

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

TRC-V097620-100G 100 g

Vanillylacetone

Ask

View Details

LC410219 20 µg

BTBD10 (NM_032320) Human Over-expression Lysate

Ask

View Details

035338-ML750 100 µL

FADS2, NT (FADS2, Fatty acid desaturase 2, Delta (6) fatty acid desaturase) (MaxLight 750) discontinued

Ask

View Details

mh31652 500 ng

LentimiRa-Off-hsa-miR-4699-3p Vector

Ask

View Details

sc-90171 10 µM

ARIH1 siRNA (h)

Ask

View Details