A 410099.1
A 410099.1 is a BIRC inhibitor, with EC50 values for BIRC2, BIRC3, BIRC4, BIRC7, and BIRC8 are 4.6, 9.2, 15.6, 19.9, and 93.9 nM, respectively[1].
Product Specifications
CAS Number
[762274-58-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
IAP
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/a-410099-1.html
Purity
99.30
Solubility
DMSO : 50.51 mg/mL (ultrasonic; warming)
Smiles
O=C([C@H]1N(CCC1)C([C@H](C2CCCCC2)NC([C@H](C)NC)=O)=O)N[C@H]3C4=CC=CC=C4CCC3.Cl
Molecular Formula
C27H41ClN4O3
Molecular Weight
505.09
Precautions
H302, H315, H319, H335
References & Citations
[1]Schwalm MP, et al Toolbox for the Generation of Chemical Probes for Baculovirus IAP Repeat Containing Proteins. Front Cell Dev Biol. 2022 May 26;10:886537.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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