Xanthohumol D
Xanthohumol D, isolated from hops, is an inhibitor of quinone reductase-2 (QR-2) with the IC50 value of 110 μM, and binds to the active site of QR-2. Xanthohumol D shows antiproliferative activity on human cancer cell lines in vitro[1][2].
Product Specifications
CAS Number
274675-25-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/xanthohumol-d.html
Purity
99.21
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=C(OC)C=C(O)C(CC(O)C(C)=C)=C1O)/C=C/C2=CC=C(O)C=C2
Molecular Formula
C21H22O6
Molecular Weight
370.40
Precautions
H302, H315, H319, H335
References & Citations
[1]Choi Y, et al. Screening natural products for inhibitors of quinone reductase-2 using ultrafiltration LC-MS. Anal Chem. 2011 Feb 1;83 (3) :1048-52.|[2]Tronina T, et al. Fungal metabolites of xanthohumol with potent antiproliferative activity on human cancer cell lines in vitro. Bioorg Med Chem. 2013 Apr 1;21 (7) :2001-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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