Human sFRP1 (recombinant)

<strong>Human sFRP1 (recombinant)</strong>_x000D_ <strong>Catalog number:</strong> B2016780_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 34 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> SARP-2, Secreted Apoptosis-related Protein 2, Secreted Frizzled-related Protein 1_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Mosa MH, Michels BE, Menche C, Nicolas AM, Darvishi T, Greten FR, Farin HF. A Wnt-Induced Phenotypic Switch in Cancer-Associated Fibroblasts Inhibits EMT in Colorectal Cancer Cancer Res. 2020 Dec 15;80(24):5569-5582._x000D_ 2: Ghoshal A, Ghosh SS. Expression, purification, and therapeutic implications of recombinant sFRP1 Appl Biochem Biotechnol. 2015 Feb;175(4):2087-103._x000D_ 3: Ren J, Wang R, Huang G, Song H, Chen Y, Chen L. sFRP1 inhibits epithelial-mesenchymal transition in A549 human lung adenocarcinoma cell line Cancer Biother Radiopharm. 2013 Sep;28(7):565-71._x000D_ 4: Zhou LB, Cao Q, Ding Q, Sun WL, Li ZY, Zhao M, Lin XW, Zhou GP, Fan WX. Transcription factor FOXC1 positively regulates SFRP1 expression in androgenetic alopecia Exp Cell Res. 2021 Jul 1;404(1):112618._x000D_ 5: Gregory KJ, Morin SM, Schneider SS. Regulation of early growth response 2 expression by secreted frizzled related protein 1 BMC Cancer. 2017 Jul 7;17(1):473._x000D_ 6: Nakamura T, Hosoyama T, Murakami J, Samura M, Ueno K, Kurazumi H, Suzuki R, Mikamo A, Hamano K. Age-related increase in Wnt inhibitor causes a senescence-like phenotype in human cardiac stem cells Biochem Biophys Res Commun. 2017 Jun 3;487(3):653-659._x000D_ 7: Nicu C, O'Sullivan JDB, Ramos R, Timperi L, Lai T, Farjo N, Farjo B, Pople J, Bhogal R, Hardman JA, Plikus MV, Ansell DM, Paus R. Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation J Invest Dermatol. 2021 Jul;141(7):1633-1645.e13._x000D_ 8: Hu H, Wang T, Pan R, Yang Y, Li B, Zhou C, Zhao J, Huang Y, Duan S. Hypermethylated Promoters of Secreted Frizzled-Related Protein Genes are Associated with Colorectal Cancer Pathol Oncol Res. 2019 Apr;25(2):567-575._x000D_ 9: Yang ZQ, Liu G, Bollig-Fischer A, Haddad R, Tarca AL, Ethier SP. Methylation-associated silencing of SFRP1 with an 8p11-12 amplification inhibits canonical and non-canonical WNT pathways in breast cancers Int J Cancer. 2009 Oct 1;125(7):1613-21._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/29291647">10: Szigeti KA, Galamb O, Kalmár A, Barták BK, Nagy ZB, Márkus E, Igaz P, Tulassay Z, Molnár B. [Role and alterations of DNA methylation during the aging and cancer] Orv Hetil. 2018 Jan;159(1):3-15. </a>_x000D_ _x000D_ <strong>Products Related to Human sFRP1 (recombinant) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>