N-Acetyl [Leu28, Leu31] neuropeptide Y (24–36)

N-Acetyl [Leu28, Leu31] neuropeptide Y (24–36) is a selective agonist of neuropeptide Y Y2 receptor. N-Acetyl [Leu28, Leu31] neuropeptide Y (24–36) attenuates cardiac vagal action in anaesthetised rats[1].

Product Specifications

CAS Number

[155709-24-3]

Product Name Alternative

Ac-[Leu28,31]-NPY (24-36)

UNSPSC

12352209

Target

Neuropeptide Y Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/n-acetyl-leu28-leu31-neuropeptide-y-24-36.html

Purity

98.03

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CC2=CC=C(C=C2)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@@H](NC(C)=O)CC(C)C)=O)=O)CC3=CN=CN3)=O

Molecular Formula

C81H131N27O19

Molecular Weight

1787.08

References & Citations

[1]Potter EK, et al. A novel neuropeptide Y analog, N-acetyl [Leu28, Leu31]neuropeptide Y- (24-36), with functional specificity for the presynaptic (Y2) receptor. Eur J Pharmacol. 1994 May 17;267 (3) :253-62.