γ-Glu-Gly (TFA)
γ-Glu-Gly TFA, a γ-glutamyl dipeptide, is a human lipid metabolite.γ-Glu-Gly TFA has a similar structure to GABA (γ-aminobutyric acid) and can act as an antagonist of excitatory amino acids[1][2][3].
Product Specifications
UNSPSC
12352209
Target
Endogenous Metabolite
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/γ-glu-gly-tfa.html
Solubility
10 mM in DMSO
Smiles
OC(CNC(CC[C@H](N)C(O)=O)=O)=O.O=C(O)C(F)(F)F
Molecular Formula
C9H13F3N2O7
Molecular Weight
318.20
References & Citations
[1]Kit-Yi Leung, et al. Regulation of glycine metabolism by the glycine cleavage system and conjugation pathway in mouse models of non-ketotic hyperglycinemia. J Inherit Metab Dis. 2020 Nov;43 (6) :1186-1198.|[2]Sonu Yadav, et al. Metabolomics shows the Australian dingo has a unique plasma profile. Sci Rep. 2021 Mar 4;11 (1) :5245.|[3]Olga A Sofyanovich, et al. Multiple pathways for the formation of the γ-glutamyl peptides γ-glutamyl-valine and γ- glutamyl-valyl-glycine in Saccharomyces cerevisiae. PLoS One. 2019 May 9;14 (5) :e0216622.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Frequently Asked Questions
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