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γ-Glu-Gly (TFA)

γ-Glu-Gly TFA, a γ-glutamyl dipeptide, is a human lipid metabolite.γ-Glu-Gly TFA has a similar structure to GABA (γ-aminobutyric acid) and can act as an antagonist of excitatory amino acids[1][2][3].

Product Specifications

UNSPSC

12352209

Target

Endogenous Metabolite

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/γ-glu-gly-tfa.html

Solubility

10 mM in DMSO

Smiles

OC(CNC(CC[C@H](N)C(O)=O)=O)=O.O=C(O)C(F)(F)F

Molecular Formula

C9H13F3N2O7

Molecular Weight

318.20

References & Citations

[1]Kit-Yi Leung, et al. Regulation of glycine metabolism by the glycine cleavage system and conjugation pathway in mouse models of non-ketotic hyperglycinemia. J Inherit Metab Dis. 2020 Nov;43 (6) :1186-1198.|[2]Sonu Yadav, et al. Metabolomics shows the Australian dingo has a unique plasma profile. Sci Rep. 2021 Mar 4;11 (1) :5245.|[3]Olga A Sofyanovich, et al. Multiple pathways for the formation of the γ-glutamyl peptides γ-glutamyl-valine and γ- glutamyl-valyl-glycine in Saccharomyces cerevisiae. PLoS One. 2019 May 9;14 (5) :e0216622.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Frequently Asked Questions

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