Herkinorin

Herkinorin is a potent and selective agonist of µ opioid receptor with a Ki of 45 nM Herkinorin is widely used for pain research[1].

Product Specifications

CAS Number

[862073-77-6]

UNSPSC

12352005

Target

Opioid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/herkinorin.html

Solubility

10 mM in DMSO

Smiles

O=C([C@H](C[C@H](OC(C1=CC=CC=C1)=O)C([C@@]23[H])=O)[C@]2(C)CC[C@@]([C@]3(C)C[C@@H](C4=COC=C4)O5)([H])C5=O)OC

Molecular Formula

C28H30O8

Molecular Weight

494.53

References & Citations

[1]Lamb K, et al. Antinociceptive effects of herkinorin, a MOP receptor agonist derived from salvinorin A in the formalin test in rats: new concepts in mu opioid receptor pharmacology: from a symposium on new concepts in mu-opioid pharmacology. Drug Alcohol Depend. 2012 Mar 1;121 (3) :181-8.