L-Cystathionine

L-Cystathionine is a nonprotein thioether and is a key amino acid associated with the metabolic state of sulfur-containing amino acids. L-Cystathionine protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs) . L-Cystathionine plays an important role in cardiovascular protection[1][2].

Product Specifications

CAS Number

[56-88-2]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Endogenous Metabolite

Type

Natural Products

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/L-Cystathionine.html

Purity

99.0

Solubility

1M HCl : 50 mg/mL (ultrasonic; adjust pH to 1 with HCl) |DMSO : < 1 mg/mL|H2O : 25 mg/mL (ultrasonic; adjust pH to 10 with NaOH) |H2O : 40 mg/mL (adjust pH to 2 with 1 M HCl)

Smiles

N[C@@H](CCSC[C@H](N)C(O)=O)C(O)=O

Molecular Formula

C7H14N2O4S

Molecular Weight

222.26

Precautions

H302, H315, H319, H335

References & Citations

[1]Amino Y, et al. Synthesis and evaluation of L-cystathionine as a standard for amino acid analysis. Biosci Biotechnol Biochem. 2017 Jan;81 (1) :95-101.|[2]Xiuli Wang, et al. L-Cystathionine Protects against Homocysteine-Induced Mitochondria-Dependent Apoptosis of Vascular Endothelial Cells. Oxid Med Cell Longev. 2019 Nov 25;2019:1253289.