Galectin-8N-IN-1

Galectin-8N-IN-1 (compound 19a) is a potent and selective galectin-8N inhibitor with a Kd value of 1.8 μM. Galectin-8N-IN-1 is a galectin-8N ligand. Galectin-8N-IN-1 can be used in research of immune system[1].

Product Specifications

CAS Number

[2667628-25-1]

UNSPSC

12352005

Target

Galectin

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/galectin-8n-in-1.html

Purity

98.09

Solubility

DMSO : ≥ 50 mg/mL

Smiles

CN1C2=CC(C(O)=O)=CC=C2N=C1CO[C@@H]3[C@H]([C@H](O[C@@H]([C@@H]3O)CO)SC4=CC(Cl)=C(C=C4)Cl)O

Molecular Formula

C22H22Cl2N2O7S

Molecular Weight

529.39

References & Citations

[1]Hassan M, et, al. Benzimidazole-galactosides bind selectively to the Galectin-8 N-Terminal domain: Structure-based design and optimisation. Eur J Med Chem. 2021 Nov 5;223:113664.