Sesamin

Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia[1][2].

Product Specifications

CAS Number

[607-80-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Stearoyl-CoA Desaturase (SCD)

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sesamin.html

Purity

99.85

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

[H][C@@]12[C@@H](C3=CC=C(OCO4)C4=C3)OC[C@]1([H])[C@@H](C5=CC=C(OCO6)C6=C5)OC2

Molecular Formula

C20H18O6

Molecular Weight

354.35

Precautions

H302, H315, H319, H335

References & Citations

[1]Cheng FC, et al. Neuroprotective effects of sesamin and sesamolin on gerbil brain in cerebral ischemia. Int J Biomed Sci. 2006 Sep;2 (3) :284-8.|[2]Shimizu S, et al. Sesamin is a potent and specific inhibitor of delta 5 desaturase in polyunsaturated fatty acidbiosynthesis. Lipids. 1991 Jul;26 (7) :512-6.