DC-LC3in-D5
DC-LC3in-D5 acts as an autophagy inhibitor by attenuating LC3B lipidation. DC-LC3in-D5 binds with LC3B. DC-LC3in-D5 disrupts the LC3B-LBP2 interaction with an IC50 of 200 nM. DC-LC3in-D5 may contribute to anti-HCV or combination researchs in cancer through inhibiting autophagy[1].
Product Specifications
CAS Number
[2868312-73-4]
UNSPSC
12352005
Target
Atg8/LC3; Autophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dc-lc3in-d5.html
Purity
98.62
Solubility
DMSO : 35.71 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1/C(C(CC(C2=C(Cl)C(Cl)=CC=C2)C1)=O)=C/NCCN3CCOCC3
Molecular Formula
C19H22Cl2N2O3
Molecular Weight
397.30
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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