E3 Ligase Ligand-linker Conjugate 137
E3 Ligase Ligand-linker Conjugate 137 is the linker and E3 ligase ligand for the PROTAC METTL3-14 degrader 1 (HY-162282), which can be used for research on acute myeloid leukemia[1].
Product Specifications
UNSPSC
12352211
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugate-137.html
Smiles
O=C(CCCCCNC1=C(C(N(C2CCC(NC2=O)=O)C3=O)=O)C3=CC=C1)N(CC4)CCN4CCO
Molecular Formula
C25H33N5O6
Molecular Weight
499.56
References & Citations
[1]Francesco Errani, et al. Proteolysis Targeting Chimera Degraders of the METTL3-14 m6A-RNA Methyltransferase. JACS Au. 2024 Feb 12;4 (2) :713-729.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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