E3 Ligase Ligand-linker Conjugate 137

E3 Ligase Ligand-linker Conjugate 137 is the linker and E3 ligase ligand for the PROTAC METTL3-14 degrader 1 (HY-162282), which can be used for research on acute myeloid leukemia[1].

Product Specifications

UNSPSC

12352211

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugate-137.html

Smiles

O=C(CCCCCNC1=C(C(N(C2CCC(NC2=O)=O)C3=O)=O)C3=CC=C1)N(CC4)CCN4CCO

Molecular Formula

C25H33N5O6

Molecular Weight

499.56

References & Citations

[1]Francesco Errani, et al. Proteolysis Targeting Chimera Degraders of the METTL3-14 m6A-RNA Methyltransferase. JACS Au. 2024 Feb 12;4 (2) :713-729.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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