ART-IN-1
Product Specifications
UNSPSC Description
ART-IN-1 (compound 7) is a selective PARP inhibitor with IC50s of 19, 22, 2.4, >100, 1.1 μM for PARP2, TNKS2, PARP10, PARP14, PARP15, respectively[1].
Target Antigen
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/art-in-1.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(OC1=CC2=C(C(NC3=C2C=CS3)=O)C=C1)C
Molecular Weight
259.32
References & Citations
[1]Maksimainen MM, et al. Analogs of TIQ-A as inhibitors of human mono-ADP-ribosylating PARPs. Bioorg Med Chem. 2021;52:116511.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-143338/ART-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-143338/ART-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2418014-98-7
Available Sizes
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