Semzuvolimab
Semzuvolimab is a human IgG1κ antibody, targeting to p55, T cell surface antigen T4/Leu-3 (CD4) . Human CD4 antibodies can neutralize HIV infection and have the potential to inhibit HAART stable HIV infection[1][2].
Product Specifications
CAS Number
[2409099-32-5]
Product Name Alternative
UB421
UNSPSC
12352203
Target
HIV
Type
Inhibitory Antibodies
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/semzuvolimab.html
Purity
95.00
Solubility
10 mM in DMSO|H2O
Smiles
[Semzuvolimab]
Molecular Weight
(145.15 kDa)
References & Citations
[1]Wang Changyi, et al. Treatment and sustained virologic remission of HIV infection by antibodies to CD4 in HAART stabilized patients. World Intellectual Property Organization, WO2018035001 A1. 2018-02-22.|[2]Semzuvolimab. IMGT/mAb-DB.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 3
Available Sizes
Curated Selection
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