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Semzuvolimab

Semzuvolimab is a human IgG1κ antibody, targeting to p55, T cell surface antigen T4/Leu-3 (CD4) . Human CD4 antibodies can neutralize HIV infection and have the potential to inhibit HAART stable HIV infection[1][2].

Product Specifications

CAS Number

[2409099-32-5]

Product Name Alternative

UB421

UNSPSC

12352203

Target

HIV

Type

Inhibitory Antibodies

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/semzuvolimab.html

Purity

95.00

Solubility

10 mM in DMSO|H2O

Smiles

[Semzuvolimab]

Molecular Weight

(145.15 kDa)

References & Citations

[1]Wang Changyi, et al. Treatment and sustained virologic remission of HIV infection by antibodies to CD4 in HAART stabilized patients. World Intellectual Property Organization, WO2018035001 A1. 2018-02-22.|[2]Semzuvolimab. IMGT/mAb-DB.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 3

Available Sizes

Curated Selection

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