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Artesunate

Product Specifications

UNSPSC Description

Artesunate is an inhibitor of both STAT-3 and exported protein 1 (EXP1).

Target Antigen

Ferroptosis; Parasite; STAT; Virus Protease

Type

Natural Products

Related Pathways

Anti-infection;Apoptosis;JAK/STAT Signaling;Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Artesunate.html

Purity

99.84

Solubility

7.5% Sodium bicarbonate : 2 mg/mL (ultrasonic;warming;heat to 60°C)|DMSO : 83.33 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL

Smiles

O=C(O[C@H]1[C@H](C)[C@]2([H])CC[C@@H](C)[C@]3([H])CC[C@@](O4)(C)OO[C@]32[C@]4([H])O1)CCC(O)=O

Molecular Weight

384.42

References & Citations

[1]Ilamathi M, et al. Artesunate as an Anti-Cancer Agent Targets Stat-3 and Favorably Suppresses Hepatocellular Carcinoma. Curr Top Med Chem. 2016;16(22):2453-63.|[2]Lisewski AM, et al. Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate. Cell. 2014 Aug 14;158(4):916-928.|[3]Wang B, et al. Artesunate sensitizes ovarian cancer cells to cisplatin by downregulating RAD51. Cancer Biol Ther. 2015;16(10):1548-56.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N0193/Artesunate-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N0193/Artesunate-SDS-MedChemExpress.pdf

Clinical Information

Launched

CAS Number

88495-63-0

Available Sizes

Curated Selection

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