PEN (rat)
PEN (rat), one of the most abundant hypothalamic neuropeptide and derived from the proprotein ProSAAS, is an endogenous ligand of GPR83[1].
Product Specifications
CAS Number
[569364-13-2]
UNSPSC
12352209
Target
G protein-coupled Bile Acid Receptor 1
Type
Peptides
Related Pathways
GPCR/G Protein
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pen-rat.html
Purity
99.24
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(N1[C@@H](CCC1)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(O)=O)C(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]2N(CCC2)C([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@H]3N(CCC3)C(CNC([C@H](CC(C)C)NC([C@H](CC(O)=O)NC([C@H](CCC(N)=O)NC([C@H](CC(O)=O)NC([C@H](C(C)C)NC([C@@H](N)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C102H169N27O33
Molecular Weight
2301.59
References & Citations
[1]Seshat M Mack, et al. Neuropeptide PEN and Its Receptor GPR83: Distribution, Signaling, and Regulation. ACS Chem Neurosci. 2019 Apr 17;10 (4) :1884-1891.|[2]Ivone Gomes, et al. Identification of GPR83 as the receptor for the neuroendocrine peptide PEN. Sci Signal. 2016 Apr 26;9 (425) :ra43.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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