HDAC6-IN-50
HDAC6-IN-50 (Compound 4) is a potent HDAC6 inhibitor with an IC50 of 35 nM. HDAC6-IN-50 can be used for the study of Parkinson's disease (PD) and Alzheimer's disease (AD) research[1].
Product Specifications
CAS Number
3060094-56-3
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hdac6-in-50.html
Smiles
O=S(N1C2=CC=C(C=C2C=C1)OCCCN3CCN(CC3)CC#C)(C4=CC=C(C=C4)C(NO)=O)=O
Molecular Formula
C25H28N4O5S
Molecular Weight
496.58
References & Citations
[1]Mireia Toledano-Pinedo, et al. Contilisant+Tubastatin A Hybrids: Polyfunctionalized Indole Derivatives as New HDAC Inhibitor-Based Multitarget Small Molecules with In Vitro and In Vivo Activity in Neurodegenerative Diseases. J Med Chem. 2024 Sep 26;67 (18) :16533-16555.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC6
Frequently Asked Questions
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