2-HBA
Product Specifications
UNSPSC Description
2-HBA is a potent inducer of NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1) which can also activate caspase-3 and caspase-10.
Target Antigen
Caspase
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-HBA.html
Purity
99.09
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(/C=C/C1=CC=CC=C1O)/C=C/C2=CC=CC=C2O
Molecular Weight
266.29
References & Citations
[1]Dinkova-Kostova AT, et al. Bis(2-hydroxybenzylidene)acetone, a potent inducer of the phase 2 response, causes apoptosis in mouse leukemia cells through a p53-independent, caspase-mediated pathway. Cancer Lett. 2007 Jan 8;245(1-2):341-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-103667/2-HBA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-103667/2-HBA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
131359-24-5
Available Sizes
Curated Selection
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