[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11)
Product Specifications
UNSPSC Description
[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist. [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) inhibits the effects of gold-protein-substance P (GPSP) and substance P (SP)[1].
Target Antigen
Neurokinin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/d-pro4-d-trp7-9-nle11-substance-p-4-11.html
Solubility
H2O
Smiles
CCCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CC3=CC=CC=C3)NC([C@@H](CC4=CNC5=C4C=CC=C5)NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@@H]6NCCC6)=O)=O)=O)=O)=O)=O)=O
Molecular Weight
1116.31
References & Citations
[1]Cathieni M M, et al. Pharmacological Evidence that Gold-Protein-Substance P Complex Activates Neurokinin NK1 Receptors[J]. Cellular Physiology & Biochemistry, 1995, 5(2):85-95.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P3805/D-Pro4-D-Trp7-9-Nle11-Substance-P-4-11-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P3805/
Clinical Information
No Development Reported
CAS Number
89430-34-2
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