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PROTAC RIPK degrader-6

Product Specifications

UNSPSC Description

PROTAC RIPK degrader-6 (example 1) is a Cereblon-based PROTAC targeting RIP Kinase degradation wherein the RIP2 kinase inhibitor is linked via a linker to a cereblon binder[1].

Target Antigen

PROTACs; RIP kinase

Type

Reference compound

Related Pathways

Apoptosis;PROTAC

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/protac-ripk-degrader-6.html

Purity

99.97

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=S(C(C(OCCOCCOCCOCCOCC(NC1=C(CN(C2C(NC(CC2)=O)=O)C3=O)C3=CC=C1)=O)=C4)=CC(C4=NC=C5)=C5NC6=CC(N=CS7)=C7C=C6)(C(C)(C)C)=O

Molecular Weight

889.00

References & Citations

[1]John David Harlin, et al. Compounds for the modulation of rip2 kinase activity. WO2017046036A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-111870/PROTAC-RIPK-degrader-6-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-111870/PROTAC-RIPK-degrader-6-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2089205-64-9

Available Sizes

Curated Selection

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