Human USAG-1 Protein, Fc Tag
USAG1 (uterine sensitization associated gene 1), also known asSOSTDC1 (sclerostin domain–containing 1), Ectodin, is a secreted protein with a glycosylated N-terminus that contains a C-terminal cysteine knot domain. This C-terminal cysteine knot domain is present in numerous growth factors, including TGFβ, NGF, PDGF, vWF, NDP, and mucin-2, and involved in dimerization, receptor binding, and signal transduction. SOSTDC1 negatively regulates BMP signaling during cellular proliferation, differentiation, and apoptosis in several biological processes (such as dentary morphogenesis, embryo implantation in the endo-metrium, and healing of bone fractures) [8]. In addition, SOSTDC1 might also involve cancer development processes through the regulation of the Wnt pathway.
Product Specifications
Background
Specifications
Accession Number
Q6X4U4-1
Expression Region
Phe 24 - Ser 206
Host
HEK293
Target
USAG-1
Conjugation
Unconjugated
Tag
C-Fc
Source
Human
Stability
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
47.2 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
1mg*1
Host or Source
HEK293
Species
Human
Protein ID
Q6X4U4-1
Preservative
Trehalose
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