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2-Phenylethyl isothiocyanate-d5

2-Phenylethyl isothiocyanate-d5 isothiocyanate-d5 is the deuterium labeled 2-Phenylethyl isothiocyanate[1]. 2-Phenylethyl isothiocyanate is a potent antifungal agent. 2-Phenylethyl isothiocyanate significantly inhibited spore germination and mycelial growth of Alternaria alternata, with a MIC (minimum inhibitory concentration) of 1.22 mM. The antifungal effect of 2-Phenylethyl isothiocyanate against Alternaria alternata might be via reduction in toxin content and breakdown of cell membrane integrity[2][3].

Product Specifications

CAS Number

912627-98-6

Product Name Alternative

2-PE ITC-d5

UNSPSC

12352005

Target

Fungal

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Purity

94.40

Solubility

10 mM in DMSO

Smiles

S=C=NCCC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H]

Molecular Formula

C9H4D5NS

Molecular Weight

168.27

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]B. J. Smith, et al. In vitro inhibition of soil microorganisms by 2-phenylethyl isothiocyanate. Plant Pathology. 4 October 2002;51 (5) :585-593.|[3]Zhang M, et al. 2-Phenylethyl Isothiocyanate Exerts Antifungal Activity against Alternaria alternata by Affecting Membrane Integrity and Mycotoxin Production. Toxins (Basel) . 2020 Feb 1512 (2) :124.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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