SPLA2 inhibitor 3

SPLA2 inhibitor 3 (Compound 6c) is a potent α-glucosidase inhibitor (IC50 = 0.0953 µM) . sPLA2 inhibitor 3 can be used for the research of diabetes[1].

Product Specifications

UNSPSC

12352005

Target

Glycosidase; Phospholipase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/spla2-inhibitor-3.html

Smiles

O=S(C1=CC=C(C(F)(F)F)C=C1)(NNC2=NC3=CC=CC=C3N=C2NNS(C4=CC=C(C(F)(F)F)C=C4)(=O)=O)=O

Molecular Formula

C22H16F6N6O4S2

Molecular Weight

606.52

References & Citations

[1]Alasmary FAS, et al. Synthesis, molecular modelling, and biological evaluation of novel quinoxaline derivatives for treating type II diabetes. J Enzyme Inhib Med Chem. 2024 Dec;39 (1) :2395985.