DMT-2'-F-iBu-G

DMT-2'-F-iBu-G (5'-DMT-2'-F-ibu-dG) is a modified oligonucleotide. 2'-deoxy-2'-fluoro-modified oligonucleotides shows high nuclease resistant and retained exceptional binding affinity to the RNA targets[1].

Product Specifications

CAS Number

[144089-96-3]

Product Name Alternative

5'-DMT-2'-F-ibu-dG

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dmt-2-f-ibu-g.html

Purity

97.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

F[C@@H]1[C@H](O)[C@@H](COC(C2=CC=C(OC)C=C2)(C3=CC=C(OC)C=C3)C4=CC=CC=C4)O[C@H]1N(C=N5)C(NC(NC(C(C)C)=O)=N6)=C5C6=O

Molecular Formula

C35H36FN5O7

Molecular Weight

657.69

Precautions

H302, H315, H319, H335

References & Citations

[1]Kawasaki AM, et al. Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets. J Med Chem. 1993 Apr 2;36 (7) :831-41.