GSPT1 degrader-4
GSPT1 degrader-4 (3) is a GSPT1 molecule glue (DC50 of 25.4 nM), with an IC50 of 39 nM for CAL51 proliferation[1].
Product Specifications
CAS Number
3034764-32-1
UNSPSC
12352005
Target
Molecular Glues
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gspt1-degrader-4.html
Smiles
CC1=CC=C(NC(OCC2=CC=C3C(C=C(CN4C5C(NC(CC5)=O)=O)N3C4=O)=C2)=O)C=C1Cl
Molecular Formula
C24H21ClN4O5
Molecular Weight
480.90
References & Citations
[1]Jinghai, Jin, et al. Fused ring compound, pharmaceutical composition, and use thereof. Patent. WO2024067792A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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